Laboratory animals

Slc:ddY

• Good growth, High fertility
• Use for studies: General multipurpose model, Vaccine national assay, Shellfish poison test, mental disorder

Slc:ICR

• Good growth, High fertility, Body type relatively large
• Use for studies: General multipurpose model, safety and efficacy testing, Immunology, Genotoxicity test

BALB/cCrSlc

• High incidence of cardiac calcinosis
• The fighting between males occurs frequently from comparatively young age.
• Use for studies: Allergy (Asthma, Dermatitis), Monoclonal antibody production, Ulcerative colitis

"Cr" is an abbreviation for "Division of Cancer Treatment, National Cancer Institute, U.S.A"

C57BL/6NCrSlc

• Low spontaneous incidence of tumor, Hair loss in infants, High incidence to male of microphthalmia and anophthalmia, Preference for alcohol
• Use for studies: Aging, Production of genetically modified animals

C57BL/6JmsSlc

• Use for studies: Production of genetically modified animals

C3H/HeSlc

• MTV(Mammary Tumor Virus): negative, Genetic retinal abnormality
• Use for studies: Hair-growth test, Skin test

C3H/HeNSlc

• MTV: negative, High susceptibility to LPS
• Use for studies: Hair-growth test, Skin test

C3H/HeYokSlc

• MTV: negative, Low susceptibility to LPS
• Use for studies: Falling-out hair model test

A/JmsSlc

• High incidence of lung tumor, Cleft palate in infant: 8.4%
• Use for studies: Antigenicity test, Infection experiment Cleft palate in 8.4%

AKR/NSlc

• Spontaneous lymphocytic leukemia:93% in female, 80% in male
• Use for studies: Photoallergy model

129X1/SvJmsSlc

• Production of ES cell
• Use for studies: Developmental engineering

DBA/1JmsSlc

• Collagen type II-induced arthritis (Drug-induced)
• Use for studies: Phylaxis, Infection immunity experiment

DBA/2CrSlc

• Audiogenic seizures in young, High incidence of cardiac calcinosis, Low production efficiency
• Use for studies: Food allergy, Parasitic infection

CBA/NSlc

• Functional defects of B-cells
• Use for studies: Local Lymph Node Assay (LLNA), Infection experiment

NC/NgaSlc

• Use for studies: Atopic dermatitis model (Drug-induced)

BALB/cSlc-nu/nu(Left)
BALB/cSlc-nu/+(Right)

• Small-sized body, Hairless(Downy hair), Athymic, Absence of T-cell function, Activity of macrophage, High activity of natural killer (NK), Curled whiskers in infant (nu/nu)
• This strain shows a wasting syndrome and dies when infected with MHV and Sendai virus in conventional circumstances.
• Use for studies: Cancer study, Xenograft transplantation

KSN/Slc

• Athymic, Absence of T-cell function, Good mammary development (nu/nu), Homo x Homo mating
• This strain was produced by Dr. Sudo and Suzuki (1984) by introducing a mutant gene (nu) into inbred DDD/1 mice.
• Use for studies: Xenograft transplantation

C57BL/10SnSlc H2b
B10. A/SgSnSlc H2a
B10. BR/SgSnSlc H2k
B10. D2/nSnSlc H2d

• Use for studies: Mechanism of action in immune function

B10. S/SgSlc H2s

• Use for studies: Mechanism of action in immune function

B6D2F1/Slc

• Use for studies: Production of genetically modified animals

CD2F1/Slc

• Use for studies: Antitumor effect with the medicine, Cells transplant

B6C3F1/Slc

• Use for studies: Long term toxicity test, Carcinogenicity test

CB6F1/Slc

• Use for studies: Cells transplant

AKITA/Slc

• Diabetes, Non-obesity, Supplied as hetero strain

C57BL/6HamSlc
-ob/ob

• Type II diabetes, Obesity, Leptin-deficient

SAMR1/TaSlc
(Non-thymus lymphoma, Control strain of SAMP strain)
SAMP1/SkuSlc
(Promotion aging, Immune function disorder, Pulmonary overinflation-related change, Senile hearing loss, Aging amyloidosis)
SAMP6/TaSlc
(Senile osteoporosis)
SAMP8/TaSlc
(Learning disorders, Memory impairment, Emotional disorder)
SAMP10/TaIdrSlc
(Learning and memory impairment with cerebral atrophy, Emotional disorder)
SAMP10-ΔSglt2
(SAMP10/TaSlc-Slc5a2slc)
(Learning and memory impairment with cerebral atrophy, Emotional disorder / Sglt2 deficiency)

• Breeding and supply entrusted by the Council for SAM Research.
• Use for studies: Anti-aging

B6.KOR/StmSlc-Apoeshl

• Hyperlipidemia
• SHL mouse is an apolipoprotein E-deficient hyperlipidemia mouse discovered in a Japanese wild-derived laboratory mouse KOR1.
• This mouse strain is congenic mouse obtained by introducing the mutagenic gene Apoeshl into C57BL/6NCrSlc mouse.
• Spontaneous model (non-genetically engineered mouse)

C.KOR/StmSlc
-Apoeshl

• Hyperlipidemia
• SHL mouse is an apolipoprotein E-deficient hyperlipidemia mouse discovered in a Japanese wild-derived laboratory mouse KOR1.
• This mouse strain is congenic mouse obtained by introducing the mutagenic gene Apoeshl into BALB/c mouse.
• Spontaneous model (non-genetically engineered mouse)

WBB6F1/Kit-KitW/
KitW-v/Slc

• Anemia, Mast cells deficiency, Gastric ulcer
• Use for studies: Gut immunity, Oxidative stress for spermatogonial stem cell

MRL/MpJmsSlc
-lpr/lpr

• SLE, Autoimmune disease, Nephritis SLE, Lymphoma, Vasculitis

(NZW×BXSB)F1/Slc

• Thrombocytopenia

NZBWF1/Slc

• SLE, Autoimmune disease, Nephritis SLE

HIGA/NscSlc

• IgA nephropathy

C57BL/6-Tg
(CAG-EGFP)
(Green mouse)

• Most tissue cells express EGFP by CAG promoter and express green fluorescence (Photo ※).

APP transgenic mice
Tau transgenic mice

APPOSK-Tg
[C57BL/6-Tg(APPOSK)]
Oligomer pathology
APPWT-Tg
[C57BL/6-Tg(APPWT)]
Control strain of APPOSK-Tg
Tau609Tg
[C57BL/6-Tg(tau609)]
Tau pathology
Tau784Tg
[C57BL/6-Tg(tau784)]
Tau pathology
Tau264Tg
[C57BL/6-Tg(tau264)]
Control strain of Tau609Tg and Tau784Tg
OSK-KI
[C57BL/6-Tg(OSK-KI)]
Producing mouse amyloid-β, Patented

C57BL/6JJmsSlc-Tg
(gpt delta)

• Use for studies: Detection of the point and deletions mutations, Genotoxicity studies including comet assays

Hos:HR-1

• Use for studies: Dermatology, Wound healing, Percutaneous absorption

NSY.B6-Tyr+,Ay/Hos

• Spontaneous type 2 diabetes model mice（ Not transgenic mice）
• These mice exhibit persistent hyperglycemia from 3 months of age onward and shows marked obesity, insulin resistance, and impaired glucose tolerance.
• They develops fatty liver, hyperlipidemia, diabetic nephropathy, etc.
• Male mice can be housed in groups.